International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2014
Gynecologic Cancer InterGroup (GCIG) consensus review for ovarian sex cord stromal tumors.
СтатьяОбзорConsensus StatementНазвание и аннотация: Перевод пока не подготовлен
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Ray-Coquard Isabelle, Brown Jubilee, Harter Philipp, Provencher Diane M, Fong Peter C, Maenpaa Johanna, Ledermann Jonathan A, Emons Gunter, Rigaud Dominique Berton, Glasspool Rosalind M, Mezzanzanica Delia, Colombo Nicoletta
Аннотация
Sex cord stromal tumors (SCST) are rare cancers of the ovarian area in adults. They constitute a heterogeneous group of tumors that develop from the sex cords and the ovarian stroma. These tumors are detected typically at an early stage, and they may recur as late as 30 years after the initial treatment. Because 70% of the patients present with stage I tumors, surgery represents the most important therapeutic arm. There are no data to support any kind of postoperative adjuvant treatment for patients with stage IA or IB SCSTs, given the indolent nature of these neoplasms and the overall good prognosis. The long natural history of the disease may lead to repeated surgical procedure should a relapse occurs. Platinum-based chemotherapy is currently used for patients with advanced stage SCSTs or recurrent disease, with an overall response rate of 63% to 80%. The indolent nature of SCSTs with the tendency for late recurrence requires long-term follow-up.