Journal of psychosomatic research · 2026
Effects of diabetes distress on glycemic level and health-related quality of life among patients with type 2 diabetes mellitus: A cross-sectional study.
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Weng Yiqing, Xu Xinhui, Ruan Minzhi, Zhu Liang, Zhu Jing, Jin Xiaoyuan, Jiang Fengyang, Wang Hongmei
Аннотация
BACKGROUND: Managing Type 2 Diabetes Mellitus (T2DM) can impose substantial psychological stress, which may impair health-related quality of life (HRQOL). Guided by Wilson and Cleary's HRQOL model, this study examines the mediating role of diabetes distress in the relationship between glycemic control and HRQOL.
METHODS: This study conducted a cross-sectional survey of 450 T2DM outpatients from three hospitals in Zhejiang Province. We employed Structural Equation Modeling (SEM) to examine the hypothesized mediation pathways, with adjustment for socio-demographic covariates.
RESULTS: Among participants, 10.89% experienced moderate or severe diabetes distress. Correlation analysis showed significant associations between glycemic levels, diabetes distress, and DSQL scores (P < 0.01). SEM results indicated that glycemic level was directly associated with DSQL scores (β = 0.167, P < 0.001); diabetes distress partially mediated the relationship between patients' glycemic level and DSQL scores (β = 0.071, P < 0.001). The indirect pathway accounted for 29.83% of the total effect.
CONCLUSION: Diabetes distress partially mediates the relationship between glycemic level and HRQOL. Integrating psychosocial support into routine diabetes management is essential for mitigating the negative impact of poor glycemic control on patient well-being.
METHODS: This study conducted a cross-sectional survey of 450 T2DM outpatients from three hospitals in Zhejiang Province. We employed Structural Equation Modeling (SEM) to examine the hypothesized mediation pathways, with adjustment for socio-demographic covariates.
RESULTS: Among participants, 10.89% experienced moderate or severe diabetes distress. Correlation analysis showed significant associations between glycemic levels, diabetes distress, and DSQL scores (P < 0.01). SEM results indicated that glycemic level was directly associated with DSQL scores (β = 0.167, P < 0.001); diabetes distress partially mediated the relationship between patients' glycemic level and DSQL scores (β = 0.071, P < 0.001). The indirect pathway accounted for 29.83% of the total effect.
CONCLUSION: Diabetes distress partially mediates the relationship between glycemic level and HRQOL. Integrating psychosocial support into routine diabetes management is essential for mitigating the negative impact of poor glycemic control on patient well-being.