Gaceta medica de Mexico · 2022

Essential thrombocythaemia.

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Barranco-Lampón Gilberto, Martínez-Castro Raúl, Arana-Luna Luara, Álvarez-Vera José Luis, Rojas-Castillejos Flavio, Peñaloza-Ramírez Rosalinda, Carballo-Zarate Adrián Alejandro, Olarte-Carrillo Irma, Minamy Jaime Israel-García, López-Salazar Javier, Navarrete Juan José, Espinosa-Partida Arturo, Ventura-Enríquez Yanet, Ruiz-Contreras Josué Isel, Aguirre-Reyes Oyuky Gissell, Anaya-Cuéllar Irene, Aguilar-Luévano Jocelyn, Díaz-Ramírez Hugo Francisco, Herrera-Olivares Wilfrido, Aguilar-Hidalgo José Antonio, Alcívar-Cedeño Luisa Ma, Hernández-Caballero Álvaro, Galaz-Cordero Lourdes Elena, Peña-Celaya José Antonio de la, Báez-Islas Pamela Elena, Bates-Martín Ramón Alberto, Cano-León Ana Ma de la Luz, Espitia-Ríos Ma Eugenia, Barbosa Diego, Morales-Adrián Javier, Pacheco Martín Jacobo, Delgado-López Nancy, Neme-Yunes Yvette, Moralws-Hernández Alba Edna, Mújica-Martínez Aldo, Pérez-Lizardi Alejandra Betsabé, Pérez-Gómez Karen Daniela, Barragán-Ibáñez Gabriel, Martínez Adolfo, Flores-Ordúñez Karen, Ramírez-Hoyos Paulina, Ángeles Rosales-López Ma de Los, Acosta-Maldonado Brenda Lizeth, Jiménez-Ochoa Marco Alejandro, Garzón-Velásquez Katheryn Betsabé, Hernández-Ruiz Eleazar, McNally-Guillén Bosco Martín, Saucedo-Montes Erick Eduardo, Aguilar-Andrade Carolina, Vivas-Arteaga Cindy Lissette, Guerra-Alarcón Lidia Virginia, Milán-Salvatierra Andrea Iracema, Campa-Monroy Dafne Itzel, Cota-Rangel Xóchitl, Estrada-Domínguez Patricia, García-Camacho Alinka Socorro, García-Castillo Carolina, Banda-García Luisa Iztacihuatl, Rodríguez-Sánchez Vania, Meillón-García Luis Antonio, Urbina-Escalante Elizabeth, Martínez-Ramírez Mario Alberto, Loera-Fragoso Sergio José, Martínez-Coronel Jorge, Zapata-Canto Nidia, Gómez-Cortés Sue Cynthia, Medina-Coral Jesús Emanuel, Mójica-Balderas Liliana, Pérez-Zúñiga Juan Manuel, Pérez Fernando Jacobo, López-Arroyo José Luis, Zazueta-Pozos Juan Francisco, Romero-Martínez Eduardo, Romero-Rodelo Hilda, Tapia-Enríquez Ana Laura, Soriano-Mercedes Emely Johanny, Salazar-Ramírez Óscar, Vilchis-González Shendel Paulina, Tepepa-Flores Fredy, Alvarado-Ibarra Martha

Аннотация

Essential thrombocythemia (ET) is a chronic Philadelphia-negative myeloproliferative neoplasm that has its main involvement in the megakaryopoietic lineage, generating sustained thrombocytosis in peripheral blood and an increase in the number of mature megakaryocytes in the bone marrow. In addition to marked thrombocytosis, it is characterized by increased thrombotic or hemorrhagic risk and the presence of constitutional symptoms. Patients with ET have a low but known risk of disease progression to myelofibrosis and/or acute leukemia. The diagnosis is made based on the 2016 WHO criteria. At present, available treatments for patients with ET are mainly aimed at minimizing the risk of thrombosis and/or bleeding.

Essential thrombocythaemia.

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Аннотация