Report on a case of giant retroperitoneal perirenal liposarcoma with kidney preservation.

Retroperitoneal liposarcoma is an uncommon malignant tumor and a subtype of soft tissue sarcoma. Early diagnosis is particularly challenging due to the tumour's location in the retroperitoneal space, which provides ample room for expansion. Symptoms typically manifest only when the tumor reaches a substantial size or invades adjacent organs. We report a case of a 61-year-old woman who underwent surgical resection for a well-differentiated liposarcoma. Computed tomography scan revealed that the mass invaded the left perirenal fascia and displaced the descending colon, pancreas, and duodenum. Complete resection of tumour masses was performed, and we opted to preserve the kidney due to no visible renal parenchymal tumour invasion. The management of retroperitoneal perirenal liposarcoma typically entails the implementation of an R0 resection. If a tumor extends into an adjacent tissue, one must consider the benefits of achieving clear surgical margins versus the risks of medical issues and reduced quality of life.