Journal of cosmetic dermatology · 2006
Topical atropine sulfate for the treatment of axillary hyperhidrosis.
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Grimalt Ramon, Domínguez Tordera Patricia, Callejas Marco A
Аннотация
BACKGROUND: Axillary hyperhidrosis does not have a low-cost, free of secondary effects, satisfactory treatment. Eccrine hidrocystomas have been successfully treated with topical atropine solution. Hypothesis Axillary hyperhidrosis could respond to the topical application of atropine solution.
METHODS: Ten patients were selected. Eight with mild pure primary axillary hyperhidrosis and two with compensatory sweating after sympathectomy. One milliliter of a water solution of atropine sulfate at 1% was applied twice a day over the affected area and massaged for 30 s. Treatment was maintained for 15 days. The results were rated using a scale from 1 to 10 of satisfaction.
RESULTS: Only 2 of the 10 treated patients responded partially to the topical application of atropine sulfate. No local or systemic secondary effects were observed.
CONCLUSIONS: The results of the study demonstrated that focal hyperhidrosis does not improve after the local application of anticholinergic drugs such as atropine sulfate.
METHODS: Ten patients were selected. Eight with mild pure primary axillary hyperhidrosis and two with compensatory sweating after sympathectomy. One milliliter of a water solution of atropine sulfate at 1% was applied twice a day over the affected area and massaged for 30 s. Treatment was maintained for 15 days. The results were rated using a scale from 1 to 10 of satisfaction.
RESULTS: Only 2 of the 10 treated patients responded partially to the topical application of atropine sulfate. No local or systemic secondary effects were observed.
CONCLUSIONS: The results of the study demonstrated that focal hyperhidrosis does not improve after the local application of anticholinergic drugs such as atropine sulfate.