Topical atropine sulfate for the treatment of axillary hyperhidrosis.

BACKGROUND

Axillary hyperhidrosis does not have a low-cost, free of secondary effects, satisfactory treatment. Eccrine hidrocystomas have been successfully treated with topical atropine solution. Hypothesis Axillary hyperhidrosis could respond to the topical application of atropine solution.

METHODS

Ten patients were selected. Eight with mild pure primary axillary hyperhidrosis and two with compensatory sweating after sympathectomy. One milliliter of a water solution of atropine sulfate at 1% was applied twice a day over the affected area and massaged for 30 s. Treatment was maintained for 15 days. The results were rated using a scale from 1 to 10 of satisfaction.

RESULTS

Only 2 of the 10 treated patients responded partially to the topical application of atropine sulfate. No local or systemic secondary effects were observed.

CONCLUSIONS

The results of the study demonstrated that focal hyperhidrosis does not improve after the local application of anticholinergic drugs such as atropine sulfate.