Cytotoxic Lesion in the Splenium of Corpus Callosum Associated with Intracranial Infection After Deep Brain Stimulation.

Cytotoxic lesions of the corpus callosum will be present in a wide range of clinical conditions. The term "cytotoxic lesions of the corpus callosum" reflects our current understanding of the underlying pathophysiology of these lesions and does not necessarily imply confinement to the splenium. Because the symptoms vary and are not specific, the clinical diagnosis can be difficult. Brain magnetic resonance imaging will be of pivotal value in the investigation. We report the case of a patient with obsessive-compulsive disorder who underwent bilateral deep brain stimulation of the nucleus accumbens and developed infection along the surgical path of both electrodes associated with a cytotoxic lesion in the splenium of corpus callosum.