Role of gender in short- and long-term outcomes after surgery for type A aortic dissection: analysis of a multicentre European registry.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Onorati Francesco, Francica Alessandra, Demal Till, Nappi Francesco, Peterss Sven, Buech Joscha, Fiore Antonio, Folliguet Thierry, Perrotti Andrea, Hervé Amélie, Conradi Lenard, Dell'Aquila Angelo M, Rukosujew Andreas, Pinto Angel G, Lega Javier Rodriguez, Pol Marek, Rocek Jan, Kacer Petr, Wisniewski Konrad, Mazzaro Enzo, Vendramin Igor, Piani Daniela, Ferrante Luisa, Rinaldi Mauro, Quintana Eduard, Pruna-Guillen Robert, Gerelli Sebastien, Acharya Metesh, Mariscalco Giovanni, Field Mark, Kuduvalli Manoj, Pettinari Matteo, Rosato Stefano, D'Errigo Paola, Jormalainen Mikko, Mustonen Caius, Mäkikallio Timo, Di Perna Dario, Juvonen Tatu, Gatti Giuseppe, Luciani Giovanni Battista, Biancari Fausto
Аннотация
METHODS: A multicentre European registry retrospectively included all consecutive TAAD surgery patients between 2005 and 2021 from 18 hospitals across 8 European countries. Early and late mortality, and cumulative incidence of aortic reoperation were compared between genders.
RESULTS: A total of 3902 patients underwent TAAD surgery, with 1185 (30.4%) being females. After propensity score matching, 766 pairs of males and females were compared. No statistical differences were detected in the early postoperative outcome between genders. Ten-year survival was comparable between genders (47.8% vs 47.1%; log-rank test, P = 0.679), as well as cumulative incidences of distal or proximal aortic reoperations. Ten-year relative survival compared to country-, year-, age- and sex-matched general population was higher among males (0.65) compared to females (0.58). The time-period subanalysis revealed advancements in surgical techniques in both genders over the years. However, an increase in stroke was observed over time for both populations, particularly among females.
CONCLUSIONS: The past 16 years have witnessed marked advancements in surgical techniques for TAAD in both males and females, achieving comparable early and late mortality rates. Despite these findings, late relative survival was still in favour of males.