American journal of ophthalmology · 2006
Multifocal choroiditis in disseminated Cryptococcus neoformans infection.
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Andreola Carla, Ribeiro Maria P D, de Carli Carla R S, Gouvea Ana Luisa F, Curi André L L
Аннотация
PURPOSE: To report an uncommon case of multifocal choroiditis as the result of disseminated Cryptococcus neoformans infection in a patient who is HIV-positive.
DESIGN: Interventional case report.
METHODS: A 27-year-old HIV-positive woman with fever, headache, and vomiting was examined. Lumbar puncture was performed and revealed C neoformans infection. Her condition evolved with sudden bilateral blindness and deafness. Ophthalmologic examination revealed multiple yellowish choroidal lesions in the posterior pole of both eyes.
RESULTS: Postmortem examination showed disseminated C neoformans infection. Histologic examination of the eyes confirmed the presence of C neoformans in the choroiditis.
CONCLUSION: Multifocal choroiditis in C neoformans infection is a rare ophthalmic manifestation. The recognition of this condition by ophthalmologists can help physicians to diagnose a disseminated and fatal disease.
DESIGN: Interventional case report.
METHODS: A 27-year-old HIV-positive woman with fever, headache, and vomiting was examined. Lumbar puncture was performed and revealed C neoformans infection. Her condition evolved with sudden bilateral blindness and deafness. Ophthalmologic examination revealed multiple yellowish choroidal lesions in the posterior pole of both eyes.
RESULTS: Postmortem examination showed disseminated C neoformans infection. Histologic examination of the eyes confirmed the presence of C neoformans in the choroiditis.
CONCLUSION: Multifocal choroiditis in C neoformans infection is a rare ophthalmic manifestation. The recognition of this condition by ophthalmologists can help physicians to diagnose a disseminated and fatal disease.
Предметные рубрики MeSH
AIDS-Related Opportunistic InfectionsAdultAntifungal AgentsAntiretroviral Therapy, Highly ActiveAntiviral AgentsBlindnessCerebrospinal FluidChoroiditisCryptococcosisCryptococcus neoformansDeafnessDrug Therapy, CombinationEye Infections, FungalFatal OutcomeFemaleHIV SeropositivityHumansSpinal Puncture