Journal of family medicine and primary care · 2022
Association between high-sensitivity-CRP and liver elastography and cardiac ischemic diseases in patients with fatty liver.
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Nayebi Morteza, Seyedian Seyed Saeed, Hashemi Seyed Jalal, Parsi Abazar, Hajiani Eskandar
Аннотация
OBJECTIVE: Inflammatory markers are among the possible contributing factors with a proposed role in hepatic and ischemic heart disease. The present study aimed to determine the association between high-sensitivity-C-reactive protein (hs-CRP), liver elastography, and cardiac ischemic diseases in patients with fatty liver.
METHODS: In this cross-sectional comparative study, 103 consecutive patients with fatty liver were enrolled to undergo angiography. They were divided into groups with and without cardiac ischemia.
RESULTS: The results demonstrated that the mean hs-CRP was 2.3 and 10.9 mg/L in normal and ischemic angiography groups, respectively (P = 0.001). According to the receiver operating characteristic (ROC) analysis, the predictive role for hs-CRP was 94.5% that had sensitivity and specificity of 95.2% and 90%, respectively, with a cut-off point of 3.1.
CONCLUSION: This study showed that there is an association between the fatty liver, cardiac ischemia, and hs-CRP level.
METHODS: In this cross-sectional comparative study, 103 consecutive patients with fatty liver were enrolled to undergo angiography. They were divided into groups with and without cardiac ischemia.
RESULTS: The results demonstrated that the mean hs-CRP was 2.3 and 10.9 mg/L in normal and ischemic angiography groups, respectively (P = 0.001). According to the receiver operating characteristic (ROC) analysis, the predictive role for hs-CRP was 94.5% that had sensitivity and specificity of 95.2% and 90%, respectively, with a cut-off point of 3.1.
CONCLUSION: This study showed that there is an association between the fatty liver, cardiac ischemia, and hs-CRP level.