European journal of gastroenterology & hepatology · 1995
Lichen planus induced by interferon-alpha-2a therapy for chronic active hepatitis C.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Barreca T, Corsini G, Franceschini R, Gambini C, Garibaldi A, Rolandi E
Аннотация
OBJECTIVE: To report the development of hepatitis C virus (HCV)-positive chronic active hepatitis with lichen planus in a patient during interferon treatment.
DESIGN: Case report and literature review.
PATIENT: A 64-year-old anti-HCV and HCV-RNA-positive woman.
INTERVENTIONS: The patient received interferon-alpha-2a treatment for histologically proven chronic active hepatitis.
RESULTS: Four months after the start of treatment the patient developed multiple cutaneous lesions on her hands, feet and back. A skin biopsy led to the diagnosis of lichen planus. The withdrawal of interferon was followed by a marked improvement in the cutaneous lesions, but not complete regression.
CONCLUSION: This case shows that HCV-positive patients with chronic active hepatitis may develop lichen planus during interferon therapy.
DESIGN: Case report and literature review.
PATIENT: A 64-year-old anti-HCV and HCV-RNA-positive woman.
INTERVENTIONS: The patient received interferon-alpha-2a treatment for histologically proven chronic active hepatitis.
RESULTS: Four months after the start of treatment the patient developed multiple cutaneous lesions on her hands, feet and back. A skin biopsy led to the diagnosis of lichen planus. The withdrawal of interferon was followed by a marked improvement in the cutaneous lesions, but not complete regression.
CONCLUSION: This case shows that HCV-positive patients with chronic active hepatitis may develop lichen planus during interferon therapy.