Journal of clinical gastroenterology · 2014
Prevalence and risk factors of functional dyspepsia: a nationwide multicenter prospective study in Korea.
СтатьяМногоцентровое исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Kim Sung Eun, Park Hyun Kyung, Kim Nayoung, Joo Young-Eun, Baik Gwang-Ho, Shin Jeong Eun, Seo Geom Seog, Kim Gwang Ha, Kim Heung-Up, Kim Hyun Young, Kim Seon Mie, Seo Ji-Hyun, Park Eun-Ha, Cho Sung-Il
Аннотация
GOALS: To evaluate the prevalence of functional dyspepsia (FD) and its risk factors.
BACKGROUND: FD is a common disorder, but its negative influences greatly affect the quality of life. The predictive factors of FD are still ambiguous.
STUDY: A total of 3399 participants underwent screening gastroscopy at one of 7 nationwide health care centers in Korea and who completed a questionnaire. Atrophic gastritis was defined by gastroscopy. Serologic Helicobacter pylori immunoglobulin G antibody was measured by enzyme-linked immunosorbent assay.
RESULTS: Of the 3399 participants who did not have organic diseases, 694 (20.4%) had dyspeptic symptoms such as epigastric pain/soreness or postprandial discomfort. Among the 694 participants, atrophic gastritis and positive H. pylori serology were found in 282 (40.6%) and 422 (60.8%), respectively; these proportions were not different from the remaining asymptomatic subjects. Multivariate analysis showed that having relatives with gastric cancer [odds ratio (OR), 1.35; 95% confidence interval (CI), 1.01-1.81], education below college (OR, 1.32; 95% CI, 1.06-1.64), and high-salt diet (OR, 1.33; 95% CI, 1.05-1.68) were associated with FD symptoms.
CONCLUSIONS: FD symptoms were frequently found in the health check-up subjects. Relatives of gastric cancer, education below college, and high-salt diet were risk factors of FD, suggesting that FD is a multifactorial disease.
BACKGROUND: FD is a common disorder, but its negative influences greatly affect the quality of life. The predictive factors of FD are still ambiguous.
STUDY: A total of 3399 participants underwent screening gastroscopy at one of 7 nationwide health care centers in Korea and who completed a questionnaire. Atrophic gastritis was defined by gastroscopy. Serologic Helicobacter pylori immunoglobulin G antibody was measured by enzyme-linked immunosorbent assay.
RESULTS: Of the 3399 participants who did not have organic diseases, 694 (20.4%) had dyspeptic symptoms such as epigastric pain/soreness or postprandial discomfort. Among the 694 participants, atrophic gastritis and positive H. pylori serology were found in 282 (40.6%) and 422 (60.8%), respectively; these proportions were not different from the remaining asymptomatic subjects. Multivariate analysis showed that having relatives with gastric cancer [odds ratio (OR), 1.35; 95% confidence interval (CI), 1.01-1.81], education below college (OR, 1.32; 95% CI, 1.06-1.64), and high-salt diet (OR, 1.33; 95% CI, 1.05-1.68) were associated with FD symptoms.
CONCLUSIONS: FD symptoms were frequently found in the health check-up subjects. Relatives of gastric cancer, education below college, and high-salt diet were risk factors of FD, suggesting that FD is a multifactorial disease.
Предметные рубрики MeSH
Abdominal PainAdolescentAdultAgedAged, 80 and overDyspepsiaEducational StatusFemaleGastritis, AtrophicGastroscopyHelicobacter InfectionsHelicobacter pyloriHumansImmunoglobulin GMaleMiddle AgedPrevalenceProspective StudiesRepublic of KoreaRisk FactorsSodium Chloride, DietaryStomach NeoplasmsSurveys and QuestionnairesYoung Adult