Journal of the American Academy of Dermatology · 1995
Repigmentation in vitiligo vulgaris by autologous minigrafting: results in nineteen patients.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Boersma B R, Westerhof W, Bos J D
Аннотация
BACKGROUND: Minigrafting is a successful therapy for localized vitiligo but has never been reported for vitiligo vulgaris.
OBJECTIVE: Our purpose was to evaluate the efficacy of minigrafting in vitiligo vulgaris.
METHODS: In 59 patients with stable vitiligo vulgaris, a minigraft test was done by implanting two minigrafts in the lesion to be grafted. Patients were selected for grafting when spread of pigment was observed within 3 months. The rate of repigmentation was evaluated by digital image analysis.
RESULTS: Twenty-three patients (36 lesions), of 24 with a positive minigraft test, were grafted. The results of 19 patients were analyzed, showing 80% to 99% repigmentation in 14 lesions, 50% to 80% repigmentation in 10 lesions, and zero to 50% repigmentation in 12 lesions. Time of observation varied from 3 to 12 months after grafting. Best results were observed after 9 to 12 months. In all patients with a positive Koebner phenomenon depigmentation of the minigrafts developed.
CONCLUSION: Autologous minigrafting is an effective therapy for stable vitiligo vulgaris in a selected group of patients.
OBJECTIVE: Our purpose was to evaluate the efficacy of minigrafting in vitiligo vulgaris.
METHODS: In 59 patients with stable vitiligo vulgaris, a minigraft test was done by implanting two minigrafts in the lesion to be grafted. Patients were selected for grafting when spread of pigment was observed within 3 months. The rate of repigmentation was evaluated by digital image analysis.
RESULTS: Twenty-three patients (36 lesions), of 24 with a positive minigraft test, were grafted. The results of 19 patients were analyzed, showing 80% to 99% repigmentation in 14 lesions, 50% to 80% repigmentation in 10 lesions, and zero to 50% repigmentation in 12 lesions. Time of observation varied from 3 to 12 months after grafting. Best results were observed after 9 to 12 months. In all patients with a positive Koebner phenomenon depigmentation of the minigrafts developed.
CONCLUSION: Autologous minigrafting is an effective therapy for stable vitiligo vulgaris in a selected group of patients.