Journal francais d'ophtalmologie · 2025
Manually dissected Bowman's layer lenticule: Novel surgical technique for peripheral ulcerative keratitis and perforations.
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Choudhary D S, Vijay U, Khan J, Kumari K, Choudhary A, Dhakad A
Аннотация
PURPOSE: To study Bowman's membrane lenticule as a novel surgical method for treatment in cases of peripheral ulcerative keratitis.
METHOD: The study was a hospital-based, single center, prospective interventional study. The study was evaluated in 30 eyes of 30 patients associated with peripheral ulcerative keratitis (PUK). For treatment, Bowman's membrane (BM) lenticule was tucked under the edges of the lesion after formation of recess around gutter. Best-corrected visual acuity (BCVA), mean epithelization time (MET), and corneal contour were measured and compared.
RESULTS: The study enrolled a total of 30 eyes of 30 patients associated with PUK, out of which 19 were males and 11 females. The mean age of patients in the study was 50.80±10.85years. The mean BCVA changed from 0.311±0.202 decimal units preoperatively to 0.118±0.127 decimal units postoperatively, the MET was 2.30±0.530weeks and the mean corneal thickness changed from a preoperative value of 233.60±115.138 microns to 433.667±46.571 microns postoperatively.
CONCLUSION: BM lenticule is a novel surgical technique which is very forcible and staunch method to treat patients suffering from PUK, including perforations. This treatment method adds to the thickness of the cornea reasonably sufficiently, reduces inflammation by acting as barrier between raw surface and inflammatory mediators, promotes nerve growth and reinforces healing process.
METHOD: The study was a hospital-based, single center, prospective interventional study. The study was evaluated in 30 eyes of 30 patients associated with peripheral ulcerative keratitis (PUK). For treatment, Bowman's membrane (BM) lenticule was tucked under the edges of the lesion after formation of recess around gutter. Best-corrected visual acuity (BCVA), mean epithelization time (MET), and corneal contour were measured and compared.
RESULTS: The study enrolled a total of 30 eyes of 30 patients associated with PUK, out of which 19 were males and 11 females. The mean age of patients in the study was 50.80±10.85years. The mean BCVA changed from 0.311±0.202 decimal units preoperatively to 0.118±0.127 decimal units postoperatively, the MET was 2.30±0.530weeks and the mean corneal thickness changed from a preoperative value of 233.60±115.138 microns to 433.667±46.571 microns postoperatively.
CONCLUSION: BM lenticule is a novel surgical technique which is very forcible and staunch method to treat patients suffering from PUK, including perforations. This treatment method adds to the thickness of the cornea reasonably sufficiently, reduces inflammation by acting as barrier between raw surface and inflammatory mediators, promotes nerve growth and reinforces healing process.