Journal of cardiology · 2020
Analysis of mortality risk following receipt of implantable cardioverter defibrillators in patients with and without heart failure.
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Caffrey James L, Wu Cho-Kai, Chang Chia-Hsuin, Lin Jou-Wei
Аннотация
BACKGROUND: Patients covered by the Taiwan National Health Insurance (NHI) program are eligible to receive an implantable cardioverter defibrillator (ICD) if diagnosed with heart failure (HF) or were at high risk of sudden cardiac death. The study was designed to evaluate the prognoses for ICD recipients with respect to contributory risks.
METHODS: ICD recipients (N=2138) from Taiwan's NHI database, for the 11-year period 2004-2014 were identified and assigned to no heart failure (NHF, n=978) or heart failure groups (HF, n=1160). The mortality rates were reported and survival trends were compared between groups.
RESULTS: The mean age of these patients was 61.8±15.2 years and 69% were men. The HF group was older (65 vs. 58 years) and had significantly more comorbidities. Pharmaceutical and medical resource utilization was also uniformly higher within the HF group. The 30-day (1.8%) and 1-year (18.4%) mortality rates among the HF patients were 3-4 times higher than in the NHF group (log rank p=0.006 and p<0.001, respectively). A coexistent major diseases score was consistently associated with a progressive mortality risk in ICD recipients overall.
CONCLUSIONS: Of those receiving ICDs, the prognosis for HF patients is poorer than for those in the NHF group which most likely reflects the fact that the HF patients were generally older with more complicated medical conditions as evident by the association between multiple major organ dysfunction and an increased risk of death.
METHODS: ICD recipients (N=2138) from Taiwan's NHI database, for the 11-year period 2004-2014 were identified and assigned to no heart failure (NHF, n=978) or heart failure groups (HF, n=1160). The mortality rates were reported and survival trends were compared between groups.
RESULTS: The mean age of these patients was 61.8±15.2 years and 69% were men. The HF group was older (65 vs. 58 years) and had significantly more comorbidities. Pharmaceutical and medical resource utilization was also uniformly higher within the HF group. The 30-day (1.8%) and 1-year (18.4%) mortality rates among the HF patients were 3-4 times higher than in the NHF group (log rank p=0.006 and p<0.001, respectively). A coexistent major diseases score was consistently associated with a progressive mortality risk in ICD recipients overall.
CONCLUSIONS: Of those receiving ICDs, the prognosis for HF patients is poorer than for those in the NHF group which most likely reflects the fact that the HF patients were generally older with more complicated medical conditions as evident by the association between multiple major organ dysfunction and an increased risk of death.