[The clinical observation of treating acne vulgaris with "xiao cuo fang"].

OBJECTIVE

To observe the clinical curative effect of Chinese medicine "xiao cuo fang" combined with adapalene gel in the treatment of acne vulgaris.

METHODS

133 patients with acne vulgaris were divided into treatment group (80 cases) and control group (53 cases) randomly. The treatment group topically applied "xiao cuo fang" combined with 0.1% adapalene gel, the control group topically applied 0.03% retinoic acid cream. After 8 weeks, we observed the reductive percentage of skin injury, the effective rate of the treatment and the incidence rate of adverse reactions.

RESULT: The average of overall skin injury, the average of inflammatory and of non-inflammatory in the treatment group reduced 82.7%, 81.0%, 84.3%, respectively, and the control group reduced 60.5%, 59.1%, 61.9%. The difference between them had obvious significance (P < 0.05). The effect rate of the treatment group was 85.0%, and the control group was 69.8%. The difference between them had obvious significance (P < 0.05). The incidence rate of adverse reaction of the treatment group was 27.5%, and the control group was 45.3%. The difference between them had obvious significance (P <0.05).

CONCLUSION

The curative effect of "xiao cuo fang" combined with adapalene gel in the treatment of acne vulgaris is precise, and the side effects are small.