Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology · 2020
[Coexistence of IgG4-related autoimmune hepatitis and inflammatory pseudotumors of the liver:a case report].
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Adachi Yasuyo, Iwata Norikazu, Adachi Yasushi, Nakamura Hiroko, Kikuchi Takefumi, Nakamura Masahiro, Mita Hiroaki, Yoshida Yukinari, Kinoshita Ichiro, Ishii Yoshifumi, Endo Takao
Аннотация
IgG4-related autoimmune hepatitis (IgG4-AIH) is characterized by hepatic inflammation and is considered an IgG4-related disease. Several inflammatory pseudotumors (IPTs) are also considered as IgG4-related diseases;however, there have been no reports of cases wherein both diseases occurred concurrently. An older adult with liver dysfunction was admitted to the hospital and was diagnosed with IgG4-AIH following a liver biopsy;IgG4-positive plasma cell infiltration in the portal tract and high serum IgG4 concentration were detected. A few months following biopsy, imaging studies revealed two IPTs in the liver. The patient was diagnosed with cryptogenic organized pneumonia several months after imaging and was treated with steroids in a different hospital. Her liver dysfunction improved, and one of the two IPTs disappeared in response to steroid treatment. The following is an account of a rare case of IgG4-AIH with IPTs of the liver.