European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
The role of concentrated growth factor (CGF) in type 1 tympanoplasty.
СтатьяНазвание и аннотация: Перевод в очереди
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Tutar Belgin, Berkiten Güler, Çelik Cem, Doğan Osman, Horat Seher Haksever, Bayraktar Fatma Gülüm, Paltura Ceki, Sarı Hüseyin, Saltürk Ziya, Uyar Yavuz
Аннотация
BACKGROUND: The aim of this study was to investigate the efficacy of concentrated growth factor (CGF) in type 1 tympanoplasty.
METHODS: This study represents a retrospective analysis of a non-randomized interventional cohort study, included 60 patients who underwent primary type 1 tympanoplasty between November 2024 and July 2025. The patients were divided into those who received only a cartilage graft (n = 30) and those who received a cartilage graft and CGF (n = 30). The incidence rates of residual tympanic membrane perforation, audiological outcomes, and postoperative infection rates were compared.
RESULTS: The incidence rate of residual perforation was significantly lower in the CGF group than in the cartilage-only group. The audiological outcomes showed no significant differences between the groups. Postoperative infection was observed less frequently in the CGF group.
CONCLUSION: CGF may represent a promising adjunct in type 1 tympanoplasty by potentially supporting graft integration and reducing residual perforation rates.
METHODS: This study represents a retrospective analysis of a non-randomized interventional cohort study, included 60 patients who underwent primary type 1 tympanoplasty between November 2024 and July 2025. The patients were divided into those who received only a cartilage graft (n = 30) and those who received a cartilage graft and CGF (n = 30). The incidence rates of residual tympanic membrane perforation, audiological outcomes, and postoperative infection rates were compared.
RESULTS: The incidence rate of residual perforation was significantly lower in the CGF group than in the cartilage-only group. The audiological outcomes showed no significant differences between the groups. Postoperative infection was observed less frequently in the CGF group.
CONCLUSION: CGF may represent a promising adjunct in type 1 tympanoplasty by potentially supporting graft integration and reducing residual perforation rates.