Arquivos de neuro-psiquiatria · 2017
Quantitative Myasthenia Gravis Score: a Brazilian multicenter study for translation, cultural adaptation and validation.
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Oliveira Ezequiel Fernandes, Valério Berenice Cataldo Oliveira, Cavalcante Valéria, Urbano Jessica Julioti, Silva Anderson Soares, Polaro Melissa Nunes, Nacif Sergio Roberto, Oliveira Claudia Santos, Resende Maria Bernadete Dutra, Oliveira Acary Souza Bulle, Oliveira Luis Vicente Franco
Аннотация
OBJECTIVE: To perform the translation, cross-cultural adaptation and validation of the Quantitative Myasthenia Gravis Score (QMGS) to Brazilian Portuguese in accordance with international ethical standards.
METHODS: The following steps were taken: (1) implementation of the translation protocol and transcultural adaptation, (2) validation of the adapted content, and (3) assessment of reliability. To check intra- and inter-observer reproducibility, each patient underwent two interviews with interviewer-A and one with B. The QMGS was compared to the Myasthenia Gravis Composite Scale and Myasthenia-specific Quality of Life Questionnaire.
RESULTS: Our study group consisted of 30 patients, with a mean age of 47.6±11.4 years and a mean duration of illness of 11.33±8.49 years. Correlation between the QMGS and MGC was very strong (r = 0.928; p < 0.001) and substantial between the QMGS and MG-QOL 15 (r = 0.737; p < 0.001).
CONCLUSION: The Brazilian Portuguese translation, and validation of the QMGS was successfully performed.
METHODS: The following steps were taken: (1) implementation of the translation protocol and transcultural adaptation, (2) validation of the adapted content, and (3) assessment of reliability. To check intra- and inter-observer reproducibility, each patient underwent two interviews with interviewer-A and one with B. The QMGS was compared to the Myasthenia Gravis Composite Scale and Myasthenia-specific Quality of Life Questionnaire.
RESULTS: Our study group consisted of 30 patients, with a mean age of 47.6±11.4 years and a mean duration of illness of 11.33±8.49 years. Correlation between the QMGS and MGC was very strong (r = 0.928; p < 0.001) and substantial between the QMGS and MG-QOL 15 (r = 0.737; p < 0.001).
CONCLUSION: The Brazilian Portuguese translation, and validation of the QMGS was successfully performed.