Brain injury · 2026
Frequency and diagnostic yield of CRPS-I in TBI: a 12-year retrospective cohort study at a Level I trauma center.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Yoon Seon Jun, Lee Jun Won, Yun Da Been, Park Tae Sung, Lee Jae Hyun, Kim Sang Hun, Lee Byeong-Ju, Yoon Jin A, Shin Yong Beom, Shin Myung-Jun, Jang Myung Hun
Аннотация
OBJECTIVE: To investigate the frequency and diagnostic yield of Complex Regional Pain Syndrome Type I (CRPS-I) among traumatic brain injury (TBI) patients and to identify objective clinical triggers and associated factors.
DESIGN: A 12-year retrospective cohort study.
SETTING: A Level I trauma center in South Korea.
PARTICIPANTS: 5,773 TBI patients admitted between January 2011 and December 2022.
MAIN OUTCOME MEASURES: CRPS-I was diagnosed using Budapest research criteria supported by three-phase bone scintigraphy (TPBS) in clinically suspected patients. We evaluated CRPS-I frequency, diagnostic yield, and associated factors via univariate analysis.
RESULTS: Of 5,773 patients, 123 underwent TPBS for clinical suspicion, confirming 24 CRPS-I cases. The observed frequency was 0.42%, with a 19.5% (24/123) diagnostic yield among suspected patients. Edema and motor limitation were present in confirmed cases. Among clinically suspected patients, those with confirmed CRPS-I were older than those without confirmed CRPS-I (63.3 vs. 53.9 years, p = 0.028), whereas global injury severity (GCS, ISS) showed no association.
CONCLUSIONS: The 0.42% frequency underestimates true CRPS-I prevalence due to selective testing. However, a 19.5% diagnostic yield reveals significant under-recognition in cognitively impaired patients when relying on symptom-based criteria. Edema and motor limitation may serve as practical triggers for adjunctive TPBS evaluation in non-communicative survivors.
DESIGN: A 12-year retrospective cohort study.
SETTING: A Level I trauma center in South Korea.
PARTICIPANTS: 5,773 TBI patients admitted between January 2011 and December 2022.
MAIN OUTCOME MEASURES: CRPS-I was diagnosed using Budapest research criteria supported by three-phase bone scintigraphy (TPBS) in clinically suspected patients. We evaluated CRPS-I frequency, diagnostic yield, and associated factors via univariate analysis.
RESULTS: Of 5,773 patients, 123 underwent TPBS for clinical suspicion, confirming 24 CRPS-I cases. The observed frequency was 0.42%, with a 19.5% (24/123) diagnostic yield among suspected patients. Edema and motor limitation were present in confirmed cases. Among clinically suspected patients, those with confirmed CRPS-I were older than those without confirmed CRPS-I (63.3 vs. 53.9 years, p = 0.028), whereas global injury severity (GCS, ISS) showed no association.
CONCLUSIONS: The 0.42% frequency underestimates true CRPS-I prevalence due to selective testing. However, a 19.5% diagnostic yield reveals significant under-recognition in cognitively impaired patients when relying on symptom-based criteria. Edema and motor limitation may serve as practical triggers for adjunctive TPBS evaluation in non-communicative survivors.