Sahel, savana, riverine and urban malaria in West Africa: Similar control policies with different outcomes.
СтатьяПоддержка NIH: внешняя программаПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Ceesay Serign J, Bojang Kalifa A, Nwakanma Davis, Conway David J, Koita Ousmane A, Doumbia Seydou O, Ndiaye Daouda, Coulibaly Tinzana F, Diakité Mahamadou, Traoré Sekou F, Coulibaly Mamadou, Ndiaye Jean-Louis, Sarr Ousmane, Gaye Oumar, Konaté Lassana, Sy Ngayo, Faye Babacar, Faye Ousmane, Sogoba Nafomon, Jawara Musa, Dao Adama, Poudiougou Belco, Diawara Sory, Okebe Joseph, Sangaré Lansana, Abubakar Ismaela, Sissako Aliou, Diarra Ayouba, Kéita Moussa, Kandeh Balla, Long Carole A, Fairhurst Rick M, Duraisingh Manoj, Perry Robert, Muskavitch Marc A T, Valim Clarissa, Volkman Sarah K, Wirth Dyann F, Krogstad Donald J
Аннотация
The study sites for the West African ICEMR are in three countries (The Gambia, Senegal, Mali) and are located within 750 km of each other. In addition, the National Malaria Control Programmes of these countries have virtually identical policies: (1) Artemisinin Combination Therapies (ACTs) for the treatment of symptomatic Plasmodium falciparum infection, (2) Long-Lasting Insecticide-treated bed Nets (LLINs) to reduce the Entomololgic Inoculation Rate (EIR), and (3) sulfadoxine-pyrimethamine for the Intermittent Preventive Treatment of malaria during pregnancy (IPTp). However, the prevalence of P. falciparum malaria and the status of malaria control vary markedly across the four sites with differences in the duration of the transmission season (from 4-5 to 10-11 months), the intensity of transmission (with EIRs from unmeasurably low to 4-5 per person per month), multiplicity of infection (from a mean of 1.0 to means of 2-5) and the status of malaria control (from areas which have virtually no control to areas that are at the threshold of malaria elimination). The most important priority is the need to obtain comparable data on the population-based prevalence, incidence and transmission of malaria before new candidate interventions or combinations of interventions are introduced for malaria control.