AJOB neuroscience · 2022
Researcher Views on Changes in Personality, Mood, and Behavior in Next-Generation Deep Brain Stimulation.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Zuk Peter, Sanchez Clarissa E, Kostick-Quenet Kristin, Muñoz Katrina A, Kalwani Lavina, Lavingia Richa, Torgerson Laura, Sierra-Mercado Demetrio, Robinson Jill O, Pereira Stacey, Outram Simon, Koenig Barbara A, McGuire Amy L, Lázaro-Muñoz Gabriel
Аннотация
The literature on deep brain stimulation (DBS) and adaptive DBS (aDBS) raises concerns that these technologies may affect personality, mood, and behavior. We conducted semi-structured interviews with researchers (n = 23) involved in developing next-generation DBS systems, exploring their perspectives on ethics and policy topics including whether DBS/aDBS can cause such changes. The majority of researchers reported being aware of personality, mood, or behavioral (PMB) changes in recipients of DBS/aDBS. Researchers offered varying estimates of the frequency of PMB changes. A smaller majority reported changes in personality specifically. Some expressed reservations about the scientific status of the term 'personality,' while others used it freely. Most researchers discussed negative PMB changes, but a majority said that DBS/aDBS can also result in positive changes. Several researchers viewed positive PMB changes as part of the therapeutic goal in psychiatric applications of DBS/aDBS. Finally, several discussed potential causes of PMB changes other than the device itself.