Pain management · 2023
Treatment with eptinezumab for migraine prevention in people with chronic migraine and medication-overuse headache: a plain language summary.
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Starling Amaal J, Kolbet Melissa, Cady Roger, Brevig Thomas
Аннотация
WHAT IS THIS SUMMARY ABOUT?: This is a summary of three articles describing preventive treatment of migraine in participants with a diagnosis of both chronic migraine and medication-overuse headache in a study called PROMISE-2 (PRevention Of Migraine via Intravenous ALD403 Safety and Efficacy-2). People living with chronic migraine and medication-overuse headache have one of the most disabling, costly, and difficult-to-treat headache disorders.
WHAT WERE THE RESULTS?: After preventive migraine treatment with eptinezumab (trade name Vyepti), participants with chronic migraine and medication-overuse headache experienced fewer migraine days, a reduced severity of migraine attacks, and a reduced use of acute medication. More participants receiving eptinezumab treatment no longer met the definition of either chronic migraine or medication-overuse headache throughout the study when compared with those receiving placebo.
WHAT DO THE RESULTS MEAN?: Eptinezumab is beneficial for people who often use acute medication(s) due to frequent headache episodes or migraine attacks.
WHAT WERE THE RESULTS?: After preventive migraine treatment with eptinezumab (trade name Vyepti), participants with chronic migraine and medication-overuse headache experienced fewer migraine days, a reduced severity of migraine attacks, and a reduced use of acute medication. More participants receiving eptinezumab treatment no longer met the definition of either chronic migraine or medication-overuse headache throughout the study when compared with those receiving placebo.
WHAT DO THE RESULTS MEAN?: Eptinezumab is beneficial for people who often use acute medication(s) due to frequent headache episodes or migraine attacks.