Revista da Sociedade Brasileira de Medicina Tropical · 2013
Correlation between microdilution, Etest, and disk diffusion methods for antifungal susceptibility testing of fluconazole against Candida sp. blood isolates.
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Menezes Everardo Albuquerque, Vasconcelos Júnior Antônio Alexandre de, Ângelo Maria Rozzelê Ferreira, Cunha Maria da Conceição dos Santos Oliveira, Cunha Francisco Afrânio
Аннотация
INTRODUCTION: Antifungal susceptibility testing assists in finding the appropriate treatment for fungal infections, which are increasingly common. However, such testing is not very widespread. There are several existing methods, and the correlation between such methods was evaluated in this study.
METHODS: The susceptibility to fluconazole of 35 strains of Candida sp. isolated from blood cultures was evaluated by the following methods: microdilution, Etest, and disk diffusion.
RESULTS: The correlation between the methods was around 90%.
CONCLUSIONS: The disk diffusion test exhibited a good correlation and can be used in laboratory routines to detect strains of Candida sp. that are resistant to fluconazole.
METHODS: The susceptibility to fluconazole of 35 strains of Candida sp. isolated from blood cultures was evaluated by the following methods: microdilution, Etest, and disk diffusion.
RESULTS: The correlation between the methods was around 90%.
CONCLUSIONS: The disk diffusion test exhibited a good correlation and can be used in laboratory routines to detect strains of Candida sp. that are resistant to fluconazole.