Cardiovascular revascularization medicine : including molecular interventions · 2025
Aortic root replacement with a mechanical valve conduit: A single-institutional experience.
СтатьяНазвание и аннотация: Перевод в очереди
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Ahmad Danial, Yousef Sarah, Serna-Gallegos Derek, Brown James A, Bonatti Johannes, Kaczorowski David, Chu Danny, Thoma Floyd, Wang Yisi, Hasan Irsa, Ogami Takuya, Sultan Ibrahim
Аннотация
BACKGROUND: There is a lack of consensus regarding the best strategy for aortic root replacement with current guidelines supporting the use of mechanical valves in younger patients when a valve repair is not possible. We sought to describe our institutional experience with mechanical aortic root replacement.
METHODS: This was a descriptive study using an institutional database of aortic root replacements with a mechanical valve composite graft performed at our center from 2010 to 2022. All patients undergoing aortic root replacements with a mechanical valve were included. Patients undergoing concomitant operations were also included and descriptive statistics were reported.
RESULTS: A total of 217 patients underwent aortic root replacement with a mechanical valve of which women comprised 26.3 %. Bicuspid aortic valves were present in 30.41 % of patients. Aortic dissection and aneurysm were observed in 20.3 % and 35.5 % of patients, respectively, while moderate to severe aortic insufficiency was seen in 62.67 % of patients. Concomitant surgeries included coronary artery bypass graft surgery in 18 % and mitral valve replacement in 7.8 % of patients. Postoperatively, 18 % of patients required prolonged ventilation, while 3.7 % and 3.2 % had postoperative stroke or required dialysis, respectively. Reoperation for mediastinal bleeding was undertaken in 12.4 % of patients. Aortic reintervention over the period of the study was needed in eight patients (3.7 %). The operative/30-day mortality was 6.9 %. Mortality was 17.5 % at a median follow-up of 4 years (1.6-6.1).
CONCLUSION: Mechanical aortic root replacement is a relatively safe procedure for aortic root pathology with institutional outcomes comparable to other centers.
METHODS: This was a descriptive study using an institutional database of aortic root replacements with a mechanical valve composite graft performed at our center from 2010 to 2022. All patients undergoing aortic root replacements with a mechanical valve were included. Patients undergoing concomitant operations were also included and descriptive statistics were reported.
RESULTS: A total of 217 patients underwent aortic root replacement with a mechanical valve of which women comprised 26.3 %. Bicuspid aortic valves were present in 30.41 % of patients. Aortic dissection and aneurysm were observed in 20.3 % and 35.5 % of patients, respectively, while moderate to severe aortic insufficiency was seen in 62.67 % of patients. Concomitant surgeries included coronary artery bypass graft surgery in 18 % and mitral valve replacement in 7.8 % of patients. Postoperatively, 18 % of patients required prolonged ventilation, while 3.7 % and 3.2 % had postoperative stroke or required dialysis, respectively. Reoperation for mediastinal bleeding was undertaken in 12.4 % of patients. Aortic reintervention over the period of the study was needed in eight patients (3.7 %). The operative/30-day mortality was 6.9 %. Mortality was 17.5 % at a median follow-up of 4 years (1.6-6.1).
CONCLUSION: Mechanical aortic root replacement is a relatively safe procedure for aortic root pathology with institutional outcomes comparable to other centers.
Предметные рубрики MeSH
HumansFemaleMaleTreatment OutcomeMiddle AgedHeart Valve ProsthesisHeart Valve Prosthesis ImplantationAortic ValveAgedRisk FactorsBlood Vessel Prosthesis ImplantationTime FactorsRetrospective StudiesDatabases, FactualAdultBlood Vessel ProsthesisPostoperative ComplicationsProsthesis DesignRisk Assessment