Georgian medical news · 2025
ASSOCIATION BETWEEN EXERCISE MODALITIES AND GLYCEMIC CONTROL IN TYPE 2 DIABETES.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Ismail M, Hassan M, Gherdaoui A, Alnaimi M, Altamimi R, Manimaran S, Jallo M, Muthukrishnan R, Kandakurthi P, Jaborova M, Shukurov F, Elsiddig Sh, Yousif T, Babker A, Osman A, Elamin A
Аннотация
BACKGROUND: Type 2 diabetes mellitus is associated with increased cardiovascular risk, with physical inactivity contributing significantly to metabolic dysfunction. This study aimed to investigate the association between physical activity status and cardiometabolic markers in patients with type 2 diabetes mellitus in the United Arab Emirates.
METHODS: This cross-sectional study was conducted at Thumbay Labs, UAE, between January and October 2025. A total of 185 participants with type 2 diabetes were stratified into active (at least 150 minutes per week for more than 3 months) (n=99) and sedentary (n=86) groups based on physical activity levels. The active group was further subclassified by exercise type: aerobic (n=70), combined (n=17), and resistance training (n=11). Anthropometric measurements and biochemical parameters including fasting glucose, HbA1c, Fructosamine, fasting insulin, HOMA-IR, and lipid profile were assessed. Mann-Whitney U test, Kruskal-Wallis test, and Spearman's correlation were used for statistical analysis.
RESULTS: The active group demonstrated significantly lower BMI (26.4 vs 28.6 kg/m², p<0.001), fasting glucose (127 vs 149 mg/dl, p<0.001), HbA1c (6.84% vs 8.07%, p<0.001), Fructosamine (303 vs 362 μmol/L, p<0.001), fasting insulin (9.03 vs 10.99 μU/mL, p=0.011), and HOMA-IR (3.0 vs 4.1, p<0.001) compared to the sedentary group. No significant differences were observed in lipid parameters. Among exercise subgroups, resistance training exhibited the most favorable metabolic profile with the lowest HbA1c (6.41%), BMI (23.01 kg/m²), and HOMA-IR (1.9). Correlation analysis revealed significant positive associations between BMI and glycemic markers as well as insulin resistance indices.
CONCLUSION: Physical activity is associated with significantly better glycemic control, insulin sensitivity, and body composition in patients with type 2 diabetes. Resistance training demonstrated particularly favorable metabolic outcomes; however, limited sample size restrict generalizability. These findings support the integration of regular physical activity into comprehensive diabetes care strategies.
METHODS: This cross-sectional study was conducted at Thumbay Labs, UAE, between January and October 2025. A total of 185 participants with type 2 diabetes were stratified into active (at least 150 minutes per week for more than 3 months) (n=99) and sedentary (n=86) groups based on physical activity levels. The active group was further subclassified by exercise type: aerobic (n=70), combined (n=17), and resistance training (n=11). Anthropometric measurements and biochemical parameters including fasting glucose, HbA1c, Fructosamine, fasting insulin, HOMA-IR, and lipid profile were assessed. Mann-Whitney U test, Kruskal-Wallis test, and Spearman's correlation were used for statistical analysis.
RESULTS: The active group demonstrated significantly lower BMI (26.4 vs 28.6 kg/m², p<0.001), fasting glucose (127 vs 149 mg/dl, p<0.001), HbA1c (6.84% vs 8.07%, p<0.001), Fructosamine (303 vs 362 μmol/L, p<0.001), fasting insulin (9.03 vs 10.99 μU/mL, p=0.011), and HOMA-IR (3.0 vs 4.1, p<0.001) compared to the sedentary group. No significant differences were observed in lipid parameters. Among exercise subgroups, resistance training exhibited the most favorable metabolic profile with the lowest HbA1c (6.41%), BMI (23.01 kg/m²), and HOMA-IR (1.9). Correlation analysis revealed significant positive associations between BMI and glycemic markers as well as insulin resistance indices.
CONCLUSION: Physical activity is associated with significantly better glycemic control, insulin sensitivity, and body composition in patients with type 2 diabetes. Resistance training demonstrated particularly favorable metabolic outcomes; however, limited sample size restrict generalizability. These findings support the integration of regular physical activity into comprehensive diabetes care strategies.