Photocoagulation of presumed histoplasmic choroiditis.

Regadless of the etiology of the disciform lesion in the presumed ocular histoplasmosis syndrome, and regardless of our ignorance as to whether the pathogenetic mechanism relates in part to hypersensitization, or can be explained solely on a mechanistic interpretation (that is, chronic vascular decompensation [9]), the question of therapy can be evaluated independently. However, our knowledge regarding the natural history of these lesions is similarly incomplete and thus, without a controlled study, e cannot compare any of the therapeutic modalities with the natural history. Therefore, we cannot make any definitive statements regarding the value of therapy, let alone compare the different modalities. For these reasons, conclusions as to the results of photocoagulation of the macular lesions in the ocular histoplasmosis syndrome must remain incomplete...