FACTORS OF AGGRESSION AT THE STAGES OF OPEN SURGICAL TREATMENT OF SEVERE FORMS OF PERITONITIS.

There are many unresolved questions regarding the features of surgical aggression in the open method of treatment of severe forms of peritonitis. There are isolated publications in the literature on the risk features of these interventions, despite the high prevalence of the problem. The purpose of this study was to study the features of surgical aggression in the open method of treatment of severe forms of peritonitis. The study included 205 patients with severe forms of purulent peritonitis treated at the Emergency Hospital in Aktobe (n=205). To assess the factors of surgical aggression, the reliability of the results was evaluated by variational statistics according to the Student's t-criterion, taking into account the degree of freedom, at p<0.05 and p<0.01, with the calculation of arithmetic averages and their average errors (M+m). The data are presented as an average value±standard deviation or median and percentiles, p-values less than 0.05 were considered significant. Based on the results obtained, it was found that the frequency of repeated laparosanation surgical interventions in one patient was 2.8±0.3 times against the background of purulent-inflammatory process in the abdominal cavity, a high degree of stress index of the regulatory systems of the body during sanitation was revealed - up to 1460.9±101.5 units, postural reactions of blood circulation and respiration in 7.55% and metabolic disorders homeostasis. Aggressive factors affecting patients and causing the risk of multiple laparosanation interventions at the stages of open surgical treatment of severe forms of peritonitis have been identified. The data obtained can be used to develop therapeutic and preventive measures to improve the results of treatment of severe peritonitis.