Arquivos de neuro-psiquiatria · 2004
Clonidine in respiratory panic disorder subtype.
Клинический случайСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Valença Alexandre M, Nardi Antonio E, Mezzasalma Marco A, Nascimento Isabella, Lopes Fabiana L, Zin Walter A, Versiani Marcio
Аннотация
OBJECTIVE: Clonidine, which inhibits locus coeruleus discharge, would seem for theoretical reasons to be a good antipanic drug. Panic disorder (PD) presents a heterogeneous cluster of symptoms and a classification based on subtypes has been suggested and the respiratory symptoms group appears as a distinct subtype.
METHOD: We report three cases of respiratory PD patients who were successfully treated with clonidine.
RESULTS: Patients obtained panic free status, reduced anxiety levels and better functioning after clonidine administration (0.30-0.45 mg/day) for 6 weeks.
CONCLUSION: Clonidine can be effective in the treatment of respiratory PD. This drug might play a role in relieving symptoms of anxiety due to noradrenergic hyperactivity in these patients.
METHOD: We report three cases of respiratory PD patients who were successfully treated with clonidine.
RESULTS: Patients obtained panic free status, reduced anxiety levels and better functioning after clonidine administration (0.30-0.45 mg/day) for 6 weeks.
CONCLUSION: Clonidine can be effective in the treatment of respiratory PD. This drug might play a role in relieving symptoms of anxiety due to noradrenergic hyperactivity in these patients.