Journal of neuroradiology = Journal de neuroradiologie · 2011
3-T high-b-value diffusion-weighted MR imaging of hyperacute ischemic stroke in the vertebrobasilar territory.
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Lettau Michael, Laible Mona
Аннотация
BACKGROUND AND PURPOSE: Diffusion-weighted imaging (DWI) is the key method for diagnosing acute ischemic stroke. Applied b values in stroke diffusion studies are usually in the range of 800-1500 s/mm², but progress in magnetic resonance (MR) technology now permits higher b values. However, it is uncertain whether high-b-value DW sequences improve the detection of acute and hyperacute ischemic lesions. The aim of this study is to explore the sensitivity of high b values vs standard b values at 3T in hyperacute stroke in the vertebrobasilar territory.
MATERIAL AND METHODS: 3-T DWI was performed in referred patients with a clinical diagnosis of hyperacute (<6h from onset) cerebral infarction using conventional MR sequences as well as DW sequences. Examinations included the usual DW sequence (b=1000 s/mm²) and two high-b-value DW sequences (b=3000 s/mm² and b=5000 s/mm²). Patients with hyperacute stroke in the posterior circulation were included if MR imaging, including the usual DW sequence, was normal or if the diagnosis was uncertain.
RESULTS: In all six studied patients, ischemic lesions were better visualized with high-b-value DWI compared with the usual DWI. On increasing the b value, DW images appeared to be noisier while white-matter tracts became progressively hyperintense.
CONCLUSION: At 3T, high-b-value DW sequences may be helpful for diagnosing hyperacute infarctions in the vertebrobasilar territory, but further studies are needed to confirm this hypothesis.
MATERIAL AND METHODS: 3-T DWI was performed in referred patients with a clinical diagnosis of hyperacute (<6h from onset) cerebral infarction using conventional MR sequences as well as DW sequences. Examinations included the usual DW sequence (b=1000 s/mm²) and two high-b-value DW sequences (b=3000 s/mm² and b=5000 s/mm²). Patients with hyperacute stroke in the posterior circulation were included if MR imaging, including the usual DW sequence, was normal or if the diagnosis was uncertain.
RESULTS: In all six studied patients, ischemic lesions were better visualized with high-b-value DWI compared with the usual DWI. On increasing the b value, DW images appeared to be noisier while white-matter tracts became progressively hyperintense.
CONCLUSION: At 3T, high-b-value DW sequences may be helpful for diagnosing hyperacute infarctions in the vertebrobasilar territory, but further studies are needed to confirm this hypothesis.