[The influence and effectiveness of hydrochloric acid infusion on the extra- and intracellular acid-base status in vivo. Experimental study on rat tissue].

The influence of HCl infusion on extra- and intracellular acid-base status of liver, brain, heart, and skeletal muscle of nephrectomized rats was investigated in vivo. The present results showed that a decrease of extracellular plasma pH was followed by similar changes of the intracellular pH of the investigated tissues and a loss of bicarbonate from extracellular and intracellular body compartment. The results lead to the conclusion that HCl seems to be a suitable agent for correction of severe metabolic alkalosis.