In vitro assessment of anti - cutaneous leishmaniasis activity of some Sudanese plants.

Examination of crude methanol extracts of four Sudanese plants (Azadirachta indica, Acacia nilotica, Balanites aegyptiaca and Allium sativa) revealed that only three species had a considerable in-vitro anti-leishmanial activity on Leishmania major promastigotes. The plants Azadrachta indica, Allium sativa, and Acacia nilotica gave a LC50 of 10.2, 4.94, and 89.38 microg/ml, respectively. Extracts of Balanites aegyptiaca had a moderate biological activity on L major promastigotes.