Meyerson's Phenomenon Surrounding a Seborrheic Keratosis: A Case Report.

Meyerson's phenomenon (MP) is a rare immune-mediated local eczematous reaction that surrounds a pre-existing lesion, including (but not limited to) melanocytic nevi, vascular malformations, nevus sebaceus, and melanoma. We report a case of MP surrounding a seborrheic keratosis that had been non-reactive for the previous 25 years. The exact pathophysiology and antigenic triggers remain unknown. Topical steroids are commonly used to treat MP. However, removal of the inciting lesion may also provide resolution.