International forum of allergy & rhinology · 2025
Allergic Fungal Rhinosinusitis Diagnosis, Management, Associated Conditions, Pathophysiology, and Future Directions: Summary of a Multidisciplinary Workshop.
СтатьяОбзорПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Roland Lauren T, Damask Cecelia, Luong Amber U, Azar Antoine, Ebert Charles S, Edwards Thomas, Cahill Katherine N, Cho Do-Yeon, Corry David, Croston Tara L, Freeman Alexandra F, Javer Amin, Khoury Paneez, Kim Jean, Koval Michael, McCoul Edward D, Mims James W, Peters Anju, Piccirillo Jay F, Ramonell Richard P, Samarasinghe Amali, Schleimer Robert P, Smith-Davidson Prestina, Spec Andrej, Wechsler Michael E, Wise Sarah K, Levy Joshua M
Аннотация
Allergic fungal rhinosinusitis (AFRS) is a unique endotype of chronic rhinosinusitis with nasal polyps (CRSwNP). Despite high recurrence rates and often more severe presenting signs compared with other subtypes of CRSwNP, research dedicated to AFRS has been lacking. Diagnostic criteria are outdated, the mechanistic relationship of AFRS to other associated diseases is unclear, and the pathophysiology of disease and risk factors for recurrence have not been well studied. In December 2023, a multidisciplinary group of rhinologists, otolaryngologists, pulmonologists, allergists, immunologists, scientists, and infectious disease experts met at the National Institute of Health to discuss unmet needs for future AFRS research and care, including patient management, diagnostic criteria, severity, pathophysiology, and related conditions. A summary of these clinical and associated research discussions is included below.