Nutritional neuroscience · 2008
Mini Nutritional Assessment in patients with Parkinson's disease: correlation between worsening of the malnutrition and increasing number of disease-years.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Barichella Michela, Villa Maria Chiara, Massarotto Arianna, Cordara Sara Elisabetta, Marczewska Agnieszka, Vairo Antonella, Baldo Cinzia, Mauri Andrea, Savardi Chiara, Pezzoli Gianni
Аннотация
OBJECTIVE: To monitor the nutritional status of patients with Parkinson's disease using the Mini Nutritional Assessment (MNA) questionnaire.
PATIENTS AND METHODS: This was a 3-year longitudinal study conducted in a national referral centre for Parkinson's disease and other movement disorders. The cohort included 61 Parkinson's disease patients, 37 men and 24 women, mean age of 70.5 +/- 5.5 years, mean duration of disease 9 +/- 6.3 years; 35 patients were followed-up after 3 years.
RESULTS: MNA score diminished from 24.9 +/- 1.6 to 24 +/- 2.5 (P = 0.02); the proportion of patients at risk of malnutrition increased from 22.9% to 34.3%. A linear correlation was observed between MNA score and the duration of disease (P = 0.0096). The dietary assessment subscore significantly diminished (8.6 versus 8.1; P = 0.0009) as did body mass index (25.9 +/- 3.5 kg/m(2) versus 27.1 +/- 3.1 kg/m(2); P = 0.001).
CONCLUSIONS: The evaluation of nutritional status should be part of the routine work-up of a Parkinson's disease patient. Dietary education should be included amongst the therapeutic measures designed to improve the general conditions in Parkinson's disease.
PATIENTS AND METHODS: This was a 3-year longitudinal study conducted in a national referral centre for Parkinson's disease and other movement disorders. The cohort included 61 Parkinson's disease patients, 37 men and 24 women, mean age of 70.5 +/- 5.5 years, mean duration of disease 9 +/- 6.3 years; 35 patients were followed-up after 3 years.
RESULTS: MNA score diminished from 24.9 +/- 1.6 to 24 +/- 2.5 (P = 0.02); the proportion of patients at risk of malnutrition increased from 22.9% to 34.3%. A linear correlation was observed between MNA score and the duration of disease (P = 0.0096). The dietary assessment subscore significantly diminished (8.6 versus 8.1; P = 0.0009) as did body mass index (25.9 +/- 3.5 kg/m(2) versus 27.1 +/- 3.1 kg/m(2); P = 0.001).
CONCLUSIONS: The evaluation of nutritional status should be part of the routine work-up of a Parkinson's disease patient. Dietary education should be included amongst the therapeutic measures designed to improve the general conditions in Parkinson's disease.