Addressing Mental Health Needs in Patients With Cancer: A Recent Systematic Review and Meta-Analysis of the Effectiveness of Nurse-Led Interventions.

BACKGROUND

Depression and anxiety are prevalent among patients with cancer, impacting their quality of life and treatment outcomes. Nurse-led interventions are promising but show variable effectiveness.

PURPOSE: This review assessed the effectiveness of nurse-led interventions in reducing depression and anxiety in patients with cancer.

METHODS

A systematic search identified studies evaluating nurse-led approaches for depression and anxiety. Meta-analysis used Cohen's d with a random-effects model, and heterogeneity was assessed using the I 2 statistic.

RESULTS

Eighteen studies (n = 2054) showed significant reductions in depression (-1.29, 95% confidence interval [CI]: -1.52 to -1.06) and anxiety (-1.31, 95% CI: -1.55 to -1.07). Effective strategies included self-care education, cognitive-behavioral therapy, and peer support. Moderate to high heterogeneity ( I2  = 70%-75%) was partly resolved through sensitivity analyses.

CONCLUSIONS

Nurse-led interventions effectively reduce depression and anxiety in patients with cancer. Integrating these strategies into oncology care and standardizing protocols can further improve outcomes.