International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
Heart failure secondary to myocarditis after SARS-CoV-2 reinfection: a case report.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Riedel Patrícia Gabriela, Sakai Vitoria Fedrizzi, Toniasso Sheila de Castro Cardoso, Brum Maria Carlota Borba, Fernandes Fernando Schmidt, Pereira Robson Martins, Baldin Camila Pereira, Baldin Cícero de Campos, Takahasi Anderson Yudi, Shiki Hugo, Krepsky Ana Maria Rocha, Macedo Damasio Trindade, Merlo Álvaro Roberto Crespo, Rohde Luis Eduardo Paim, Joveleviths Dvora
Аннотация
INTRODUCTION: Cardiac involvement in COVID-19 can range from mild damage to severe myocarditis. The precise mechanism by which COVID-19 causes myocardial injury is still unknown. Myocarditis following administration of COVID-19 vaccines, especially those based on mRNA, has also been described. However, no reports of heart failure following reinfection with SARS-CoV-2 in patients immunized with an inactivated vaccine have been identified.
CASE DESCRIPTION: The patient was a 47-year-old male construction worker of African descent, with type II diabetes and a history of infection by SARS-CoV-2 in December 2020 and May 2021, confirmed by RT-PCR. He received two doses of an inactivated vaccine against COVID-19. Between the two COVID-19 episodes with positive RT-PCR, he had two episodes of bacterial lung infection. After the second episode of SARS-CoV-2 infection, he was diagnosed with severe heart failure as a sequela of myocarditis.
CONCLUSION: It is essential to perform a thorough follow-up after infection with SARS-CoV-2 since, even with proper immunization, it is possible that the patient was reinfected and suffered severe cardiac sequelae as a consequence. The hypothesis of an etiology associated with the use of an inactivated vaccine against COVID-19, with a potential immune enhancement mechanism following reinfection with SARS-CoV-2, cannot be rejected.
CASE DESCRIPTION: The patient was a 47-year-old male construction worker of African descent, with type II diabetes and a history of infection by SARS-CoV-2 in December 2020 and May 2021, confirmed by RT-PCR. He received two doses of an inactivated vaccine against COVID-19. Between the two COVID-19 episodes with positive RT-PCR, he had two episodes of bacterial lung infection. After the second episode of SARS-CoV-2 infection, he was diagnosed with severe heart failure as a sequela of myocarditis.
CONCLUSION: It is essential to perform a thorough follow-up after infection with SARS-CoV-2 since, even with proper immunization, it is possible that the patient was reinfected and suffered severe cardiac sequelae as a consequence. The hypothesis of an etiology associated with the use of an inactivated vaccine against COVID-19, with a potential immune enhancement mechanism following reinfection with SARS-CoV-2, cannot be rejected.