Nutrients · 2025
Steatotic Liver Disease in Older Adults: Clinical Implications and Unmet Needs.
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Clayton-Chubb Daniel, Kemp William W, Majeed Ammar, Lange Peter W, Fitzpatrick Jessica A, Vaz Karl, Lubel John S, Hodge Alexander D, Ryan Joanne, McNeil John J, Owen Alice J, Woods Robyn L, Roberts Stuart K
Аннотация
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the commonest cause of chronic liver disease worldwide. Its incidence has been increasing rapidly, alongside the growing epidemics of type 2 diabetes mellitus and overweight/obesity. Global population age has also been increasing in parallel, and predictions indicate there will be more than 2 billion persons aged over 65 by the year 2050. The interplay between MASLD and other health conditions of older persons has been a focus of recent research. In this narrative review, we aim to describe its prevalence; clinical and sociodemographic associations; and outcomes for older persons, all of which are of significant importance when considering public health messaging as well as screening and counselling individual older adults.