[Association of the degree of bronchial epithelial dysplasia to the serum level of non-enzymatic antioxidants].

The serum levels of non-enzymatic antioxidants were studied in patients with chronic nonspecific lung diseases with first-to-third-degree dysplasia of the bronchial epithelium (BE) before and after therapeutic correction. The development of BE dysplastic changes was ascertained to cause a considerable reduction in the content of antioxidant vitamin A. During the therapy contributing to reversal of BE dysplastic alterations, there was an increase in the serum levels of vitamin A and uric acid in patients with simple chronic bronchitis with both first- and second-degree dysplasia. If no therapeutic effect occurred, the systemic level of the antioxidants remained unchanged.