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Movement disorders clinical practice · 2026

Longitudinal Associations between Depression, Daytime Sleepiness, and Caregiver Strain in Parkinson's Disease.

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Holden Sarah, Lane Sean P, Christopher Madison, Mann Lisa, Carter Julie H, Quinn Joseph, Xu Jiayun

Аннотация

OBJECTIVE: Examine the longitudinal relationship between caregiver strain and Parkinson's patient depression, daytime sleepiness, and treatment with dopamine agonists and antidepressants.

BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disorder, in which family caregivers play an integral role in patient care. Depression and daytime sleepiness in PD patients have been shown to influence caregiver strain.

METHODS: This study was a longitudinal analysis of PD patient sleep and depression measures, and a measure of caregiver strain. Strain scores were modeled as a function of: accumulated time between visits, PD patient depression and sleep scores, and their interactions with time.

RESULTS: Caregiver strain increased over time, with patient depression and daytime sleepiness positively associated with greater caregiver strain.

CONCLUSIONS: Patient depressive symptoms consistently predicted caregiver strain, highlighting the central role of patient depression in caregiver well-being. Routine caregiver evaluations during patient visits facilitate timely interventions that benefit patients and caregivers.

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

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