Медицинская библиотека · Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2011

[Correlation between serum growth differentiation factor-15 and TIMI risk scores in patients with unstable angina pectoris].

Deng Ming-yao, Wu Guo-ping, Feng Xu-xia, Luo Jiang-bin

Аннотация на английскомСтатьяПеревод пока не подготовлен

Аннотация

OBJECTIVE

To explore the correlation between serum levels of growth differentiation factor-15 (GDF-15) and Thrombolysis in Myocardial Infarction (TIMI) risk scores in patients with unstable angina pectoris (UA).

METHODS

The serum levels of GDF-15 in 97 patients with UA and 30 healthy volunteers were measured using enzyme-linked immunosorbent assay (ELISA) and compared between 3 patient groups with different TIMI scores to analyze relationship between serum GDF-15 levels and TIMI risk scores.

RESULTS

The serum levels of GDF-15 in UA patients were significantly higher than those in the healthy volunteers (P<0.01). GDF-15 levels also differed significantly between patients with different TIMI scores (P<0.01), and showed a significant positive correlation to TIMI risk scores.

CONCLUSION

Serum levels of GDF-15 can be used as an index for evaluating the severity of UA.

Для цитирования: Deng Ming-yao, Wu Guo-ping, Feng Xu-xia, Luo Jiang-bin. [Correlation between serum growth differentiation factor-15 and TIMI risk scores in patients with unstable angina pectoris].. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 2011.

Предметные рубрики MeSH

Aged Angina, Unstable Female Growth Differentiation Factor 15 Humans Male Middle Aged Risk Assessment Severity of Illness Index Thrombolytic Therapy

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