Transcatheter mitral repair according to the cause of mitral regurgitation: real-life data from the Spanish MitraClip registry.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Pascual Isaac, Arzamendi Dabit, Carrasco-Chinchilla Fernando, Fernández-Vázquez Felipe, Freixa Xavier, Nombela-Franco Luis, Avanzas Pablo, Serrador Frutos Ana María, Pan Manuel, Cid Álvarez Ana Belén, Hernández-Antolín Rosa Ana, Andraka Ikazuriaga Leire, Cruz-González Ignacio, Díez Gil José Luis, Alcasena Juango María Soledad, Berenguer Jofresa Alberto, Alonso-Briales Juan H, Li Chi Hion, Benito González Tomás, Regueiro Ander, Armijo Germán, León Víctor, Amat-Santos Ignacio J, Romero Miguel, Trillo Nouche Ramiro, Fernández-Golfín Covadonga, Ruiz Gómez Lara, Campos-Arjona Rafael, Millán Xavier, Garrote Coloma Carmen, Sanchis Laura, Jiménez-Quevedo Pilar, Morís César, Hernández-García José María, Serra Antonio, Pérez de Prado Armando, Estévez-Loureiro Rodrigo
Аннотация
METHODS: Observational, multicenter, and prospective study with consecutive patient inclusion. The primary endpoint was the combination of all-cause mortality and new readmissions due to heart failure after 1 year. We compared clinical and procedural characteristics and the event rate for each MR group. We performed a multivariate analysis to identify predictive variables for the primary endpoint.
RESULTS: A total of 558 patients were included: 364 (65.2%) with functional etiology, 111 (19.9%) degenerative and 83 (14.9%) mixed. The mean age was 72.8±11.1 years and 70.3% of the sample were men. There were 95 (17%) events in the overall sample. No significant differences were found in the 3 groups in the number of primary outcome events: 11 (11.3%) in degenerative MR, 71 (21.3%) in functional MR, and 13 (18.1%) in mixed MR (P=.101). Independent predictors were functional class (P=.029), previous surgical revascularization (P=.031), EuroSCORE II (P=.003), diabetes mellitus (P=.037), and left ventricular ejection fraction (P=.015).
CONCLUSIONS: This study confirms the safety and efficacy of TMVR with MitraClip irrespective of MR etiology in real-life data and shows the main factors related to prognosis during the first year of follow up.