Biomarkers in medicine · 2017
Relationship between monocyte-to-lymphocyte ratio and coronary plaque vulnerability in patients with stable angina.
Клиническое исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Fan Zeyuan, Ji Hanhua, Li Yang, Jian Xinwen, Li Li, Liu Tao
Аннотация
AIM: To investigate the relationship between monocyte-to-lymphocyte ratio (MLR) and plaque vulnerability assessed by virtual histology intravascular ultrasound in patients with stable angina.
METHODS: 133 patients with stable angina were enrolled.
RESULTS: MLR was found to be an independent risk factor of thin cap fibrous atheroma (OR: 2.61; p = 0.025). MLR could differentiate thin cap fibrous atheroma with a sensitivity of 73.7% and a specificity of 61.8%. MLR level was positively correlated with the percentage of necrotic core (NC) area at the sites of minimum lumen area and the largest NC area, and positively related to the percentage of NC volume.
CONCLUSION: Circulating MLR level has potential in identifying the vulnerable plaques in the setting of stable angina.
METHODS: 133 patients with stable angina were enrolled.
RESULTS: MLR was found to be an independent risk factor of thin cap fibrous atheroma (OR: 2.61; p = 0.025). MLR could differentiate thin cap fibrous atheroma with a sensitivity of 73.7% and a specificity of 61.8%. MLR level was positively correlated with the percentage of necrotic core (NC) area at the sites of minimum lumen area and the largest NC area, and positively related to the percentage of NC volume.
CONCLUSION: Circulating MLR level has potential in identifying the vulnerable plaques in the setting of stable angina.