[Various problems of transformation of migraine].

Fifty-four patients aged 25 to 66 years suffering from hemicrania were examined. 21 patients showed certain changes in the clinical picture and course of hemicrania itself: enhancement of paroxysms or transformation of one form of hemicrania to the other one, more severe (e.g. a simple form transforms to an ophthalmic or an associated one). In 15 patients, ++vegeto-dystonic manifestations associated mostly with a significant reduction of migrainous paroxysms themselves and, more rarely, with their dramatic enhancement began with time to play the leading part in the disease clinical picture. Superimposition of essential hypertension or atherosclerosis was also coupled with changes in the course of hemicrania, in particular by an increase of the period of cephalgia and appearance of constant headaches.