Evidence-based complementary and alternative medicine : eCAM · 2013
Antiulcerogenic Activity of the Hydroalcoholic Extract of Leaves of Croton campestris A. St.-Hill in Rodents.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Júnior Francisco E B, de Oliveira Dayanne R, Bento Elizângela B, Leite Laura H I, Souza Daniele O, Siebra Ana Luiza A, Sampaio Renata S, Martins Anita O P B, Ramos Andreza G B, Tintino Saulo R, Lacerda-Neto Luiz J, Figueiredo Patricia R L, Oliveira Larissa R, Rodrigues Cristina K S, Sales Valterlúcio S, Figueiredo Francisco R S D N, Nascimento Emmily P, Monteiro Alefe B, Amaro Erika N, Costa José G M, Douglas Melo Coutinho Henrique, de Menezes Irwin R A, Kerntopf Marta R
Аннотация
Croton campestris A. St.-Hill., popularly known as "velame do campo," is a species native to the savannah area of Northeast Brazil, which is used by traditional communities in folk medicine for variety of health problems, especially detoxification, inflammation, and gastritis. The hydroalcoholic extract of C. campestris leaves (HELCC) was assessed for its antiulcerogenic effect in gastric lesion models and effect on intestinal motility in mice, and possible mechanisms of action were examined. HELCC showed significant gastroprotective action in all models of gastric ulcer evaluated; the results suggest that this action probably involves the nitric oxide pathway. HELCC did not show alteration of intestinal motility in mice. It was also found that C. campestris represents a promising natural source with important biological potential, justifying some of its uses in folk medicine.