Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology · 2005
[Abnormalities in stomach and duodenal ulcer immunoregulation].
Аннотация на английскомСтатьяНазвание и аннотация: Оригинал на русском
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Paltsev A I, Chernykh E R, Lebedev A G
Аннотация
The effect of the immunity state on the clinical course of stomach ulcer was studied. The study involved 50 patients (38 men and 12 women being 17-67 years old) with stomach ulcer (n = 14) and duodenal ulcer (n = 36) in the acute condition and 25 healthy blood donors. Twenty-seven patients underwent an immunology study. It was revealed that the evident increase of circulatory lymphocyte apoptosis (> 10), which is associated with the depression of their proliferative activity in vitro culture, is recorded with 40.7% of patients (11/27). It was also revealed that a high level of circulatory lymphocyte apoptosis and apoptosis-associated dysfunctions are found more frequently in people with long-term and complicated clinical course.