Genitourinary neurofibromas: clinical significance.

We describe 2 unusual cases of genitourinary neurofibromas. In 1 case a large solitary neurofibroma developed on the glans penis and in the other case a plexiform neurofibroma of the pelvis was present in young women with von Recklinghausen's disease. Each case represents either end of the spectrum of urologic involvement by this rare tumor. The solitary neurofibroma requires only local excision but the plexiform neurofibroma, causing urinary obstruction, necessitates urinary diversion. Recurrence and malignant degeneration, while virtually unheard of in the former, are relatively common in the latter. The prognosis of each type is discussed.