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DOI 10.1007/s13205-023-03849-9

Медицинская библиотека · Drug news & perspectives · 2007

Molecule of the Month. Dimebolin hydrochloride.

Arabzadeh Ehsan, Shirvani Hossein, Masjedi Mohammad Reza, Ghanei Mostafa, Hofmeister Martin, Rostamkhani Fatemeh

Клиническое исследование II фазыСтатьяМногоцентровое исследованиеРандомизированное исследованиеПеревод пока не подготовлен

Аннотация

Navigating Surgical Complexities associated with a case of Adenotonsillectomy in Arnold Chiari Malformation type 2. Arnold-Chiari or Chiari malformations (ACM) describe a group of deformities of the posterior fossa and hindbrain, which includes the cerebellum, pons, and medulla oblongata. Sleep-disordered breathing is a known but poorly evaluated comorbidity in patients with ACM. Obstructive sleep apnoea (OSA) in children is mainly caused by tonsillar and adenoid hypertrophy, and surgical resection of the palatine tonsils and adenoids is indicated depending on OSA severity. A 4-year-old male child suffering from Arnold Chiari type 2 malformation presented to us in OPD with Severe OSA. Clinical and endoscopic examination revealed presence of Grade 4 adenoids tissue and Grade 4 tonsillar hypertrophy. Patient was planned to undergo Coblation adenoidectomy and Tonsillectomy with Uvulopalatoplasty for the management of OSA. Patient tolerated the procedure well and extubating was un-eventful. Patient was kept in PICU for overnight observation and was discharged on next day without any major complications. Patient of Arnold Chiari malformation type 2 presenting with severe OSA due to peripheral cause like Chronic adenoid and tonsillar hypertrophy present an operative challenge due to nil neck extension and minimal oral cavity space. The key is that ACM 2 along with its complications, such as difficult airway, increased intracranial pressure, and autonomic dysfunction, makes it very challenging and requires well-structured and disciplined management by combined anaesthesiology, neurology, and operative team which emphasize on preoperative, intraoperative, and postoperative complications and its timely management.

Для цитирования: Arabzadeh Ehsan, Shirvani Hossein, Masjedi Mohammad Reza, Ghanei Mostafa, Hofmeister Martin, Rostamkhani Fatemeh. Molecule of the Month. Dimebolin hydrochloride.. Drug news & perspectives. 2007. DOI: 10.1007/s13205-023-03849-9.

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