The Thoracic and cardiovascular surgeon · 2025
Postoperative Atrial Fibrillation after Aortic Valve Replacement: An Isolated Episode?
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Varela Barca Laura, De Antonio Antón Nieves, Auquilla Luzuriaga Hugo, Gomez Alonso Esperanza, Roldan Martinez Maria, Monguió Santín Emilio, Alfonso Manterola Fernando, Reyes Copa Guillermo
Аннотация
OBJECTIVES: Postoperative atrial fibrillation (POAF) is a frequent entity after cardiac surgery. However, its potential relationship with adverse outcomes and permanent arrhythmias remains uncertain. We sought to assess the relationship between the occurrence of atrial fibrillation (AF) in the postoperative period and its long-term recurrence.
METHODS: Patients who underwent aortic valve replacement (AVR) with a biological prosthesis between 2005 and 2023 were analyzed at our center. The incidence of atrial fibrillation in the postoperative period and the factors associated with its occurrence, as well as its long-term recurrence and related risk factors, were analyzed.
RESULTS: The incidence of POAF was 22%. Postoperative renal insufficiency (p < 0.001) and chronic obstructive pulmonary disease (COPD) (p = 0.047) were identified as risk factors. During long-term clinical follow-up (mean 6.5 ± 4.5 years), 20.4% of patients without any previous arrhythmia episodes developed AF, whereas the incidence was 40.4% in those with atrial fibrillation in the postoperative period (Hazard Ratio [HR] = 2.18 [1.33-3.56]; p = 0.002). AF during follow-up was independently associated with age (HR = 1.05), COPD (HR = 3.22), and POAF (HR = 1.9). In addition, there was an apparent association between permanent AF during follow-up and long-term mortality, which approached statistical significance (HR = 1.4 [95% CI: 0.9-1.8]; p = 0.06).
CONCLUSION: POAF is a frequent complication following AVR and is significantly associated with an increased risk of developing permanent AF during long-term follow-up. Multivariate analysis identified renal insufficiency and COPD as independent predictors of POAF, while age and COPD were independently associated with long-term AF. Additionally, there was a trend toward an association between permanent AF and increased long-term mortality.
METHODS: Patients who underwent aortic valve replacement (AVR) with a biological prosthesis between 2005 and 2023 were analyzed at our center. The incidence of atrial fibrillation in the postoperative period and the factors associated with its occurrence, as well as its long-term recurrence and related risk factors, were analyzed.
RESULTS: The incidence of POAF was 22%. Postoperative renal insufficiency (p < 0.001) and chronic obstructive pulmonary disease (COPD) (p = 0.047) were identified as risk factors. During long-term clinical follow-up (mean 6.5 ± 4.5 years), 20.4% of patients without any previous arrhythmia episodes developed AF, whereas the incidence was 40.4% in those with atrial fibrillation in the postoperative period (Hazard Ratio [HR] = 2.18 [1.33-3.56]; p = 0.002). AF during follow-up was independently associated with age (HR = 1.05), COPD (HR = 3.22), and POAF (HR = 1.9). In addition, there was an apparent association between permanent AF during follow-up and long-term mortality, which approached statistical significance (HR = 1.4 [95% CI: 0.9-1.8]; p = 0.06).
CONCLUSION: POAF is a frequent complication following AVR and is significantly associated with an increased risk of developing permanent AF during long-term follow-up. Multivariate analysis identified renal insufficiency and COPD as independent predictors of POAF, while age and COPD were independently associated with long-term AF. Additionally, there was a trend toward an association between permanent AF and increased long-term mortality.