[The sensitivity to antibiotics of Corynebacterium non diphtheriae isolated in hospitals of Rostov-on-Don and the Rostovskaia oblast.].

The purpose of study is to analyze sensitivity of various species Corynebacterium non diphtheriaе to antibacterial pharmaceuticals. The strains of C. non diphtheriae are separated from patients with pathology of respiratory and urogenital tract and also from individuals subjected to preventive examination. The sensitivity to antibacterial pharmaceuticals was determined using technique of serial dilution in fluid growth medium on the basis values of minimal inhibitory concentration (mg per l). It is established that the most efficient antibacterial pharmaceuticals in the case of strains C. non diphtheriae proved to be Vancomycin, Cefazolin and Cefotaxime in general. In case of such particular species as С. pseudodiphtheriticum -- Cefazolin, Cefotaxime and Gentamycin; С.pseudotuberculosis -- Vancomycin, Cefazolin, Cefotaxime and Gentamycin; C. xerosis -- Cefotaxime; С.striatum -- Cefazolin and и Rifampicin. The least efficiency was manifested for strains C. non diphtheriae by Benzylpenicillin and Lincomycin in general. In case of such particular species as С. pseudodiphtheriticum and С. pseudotuberculosis -- Lincomycin and Erythromycin; C. xerosis and С. striatum -- Benzylpenicillin, Lincomycin and Erythromycin. In case of various species of C. non diphtheriae Сephalosporins (Cefotaxime and Cefazolin) can be recommended as pharmaceuticals of choice and Gentamycin and Vancomycin as reserve pharmaceuticals.